Activity Without Receptor Binding
KPV is a naturally occurring tripeptide (H-Lys-Pro-Val-OH), derived from the C-terminal fragment (position 11–13) of the alpha-MSH molecule. Unlike the full peptide, it does not bind to melanocortin receptors — the core region required for that (His-Phe-Arg-Trp) is entirely absent from the tripeptide. Instead, it acts intracellularly by inhibiting NF-κB and MAPK signaling pathways.What Researchers Use It For
In laboratory settings, KPV is used to study inflammation-associated cell signaling, particularly in models of intestinal barrier function and epithelial inflammatory regulation. Its uptake via the di-/tripeptide transporter PepT1 makes it an established tool in tripeptide transport research.Quality You Can Measure
Every batch is tested for ≥98.9% purity via HPLC and mass spectrometry and shipped with a certificate of analysis.Purity≥98.9%
FormLyophilized Powder
Molecular FormulaC₁₆H₃₀N₄O₄
StorageCool & dry (2–8°C)
For research purposes only. Not intended for human consumption.
Reviews
No reviews yet — as a newer shop we're still collecting our first ones. Until then, here's what we stand behind: